Buteyko Clinical Trials

Buteyko Clinical Trials

Summary of International Buteyko Clinical Trials

There are currently twelve published studies investigating the Buteyko Method as a treatment for asthma, including four studies in collaboration with Patrick McKeown. All studies concluded a significant improvement to asthma control with a number of trials reporting a reduction in the need for inhaled corticosteroid by 50% within three to six months.

In 2014, breathing exercises from the Buteyko and Papworth method were awarded an evidence level rating of ‘A’ by the Global Initiative for Asthma (GINA)- a world body of asthma experts – which is the highest grade that GINA assigns to any form of treatment. This development is excellent news for children and adults with asthma and paves the way for techniques like the Buteyko Method to be recommended by doctors and pulmonologists as an adjunct to conventional management.

The current valid edition of the British Thoracic Society (BTS/SIGN) Asthma Management Guidelines published in 2016, gave the evidence for the Buteyko Method, the highest evidence grade of 1++ in respect to their ability to reduce asthma symptoms and improve quality of life (as an adjuvant to pharmacotherapy). Click here to access BTS asthma guidelines.

1. Effect of Buteyko breathing exercise in newly diagnosed asthmatic patients. Prasanna K, Sowmiya K, Dhileeban C. Int J Med Public Health 2015;5:77–81

The results of this study support the effectiveness of Buteyko breathing exercise over the standard treatment in the newly diagnosed asthmatic patients. There was a statistically significant improvement of daily Asthma Control and PEFR in the group who did Buteyko breathing exercise for 2 months over the control group. With an intervention that is safe, equally efficacious and cheap, it is possible to use this Buteyko breathing technique as a primary treatment method in the management of asthmatic patients at the primary health care level itself.

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2. Efficacy of non-invasive respiratory techniques in the treatment of children with bronchial asthma: a randomized controlled trial. Ragab K Elnaggar, Mohammed A Shendy. Bulletin of Faculty of Physical Therapy. Year: 2016, Volume: 21, Issue: 1, Page: 1-10.

This study demonstrated that the Buteyko Breathing Technique and the TLPT can effectively improve the total serum IgE, the ventilatory function in terms of FVC, FEV1, PEF, FEF25–75% and FEV1/FVC, and C-ACT scores in children with bronchial asthma. However, Buteyko breathing was more significantly effective compared with the TLPT.

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3. Comparison of the effects of Buteyko and Pranayama breathing techniques on quality of life in patients with asthma – a randomized controlled Prem V1, Sahoo RC, Adhikari P. Trial. Clin Rehabil. 2013 Feb;27(2):133-41.

The baseline characteristics were similar in all three groups. Post intervention, the Buteyko group showed better trends of improvement (mean (95% confidence interval), P-value) in total Asthma Quality of Life Questionnaire score than the pranayama (0.47 (-0.008-0.95), P = 0.056) and control groups (0.97 (0.48-1.46), P = 0.0001). In comparison between the pranayama and control groups, pranayama showed significant improvement (0.50 (0.01-0.98), P = 0.042) in total Asthma Quality of Life Questionnaire score. The Buteyko group showed better trends of improvement in quality of life and asthma control than the group performing the pranayama breathing exercise.

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4. Role of Buteyko breathing technique in asthmatics with nasal symptoms. Clinical Otolaryngology. 2013, April;38(2):190-191

In collaboration with the University of Limerick, Patrick McKeown was the instructor in a clinical study investigating the Buteyko Method as a treatment for rhinitis in asthma. Results showed a 70% reduction of nasal symptoms in participants, including snoring, loss of smell, nasal congestion and difficulty breathing through the nose.

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5. Effect of Buteyko breathing technique on patients with bronchial asthma. Department of Physical Therapy, Cairo University, Egypt. Chest Department, Faculty of Medicine, Ain Shams University, Egypt. Faculty of Physical Therapy, Cairo University, Egypt. Hassan Z, Riad N, Ahmed F. Available online 31 January 2013

Taken from the paper: ‘Even though no study has indicated exactly why Buteyko is so effective at controlling asthma, if a drug could show these results, then it is likely that it would be used widely in asthma control. In the present study, the result of Buteyko breathing technique showed a decrease in asthma daily symptoms with 52% and 0.8% in group (A) and (B), respectively. The results of this study support the good effect of Buteyko Breathing Technique on patients with bronchial asthma. It significantly decrease the recurrence and the severity of the main bronchial asthma symptoms (nocturnal waking, morning symptoms activity limitation, shortness of breath, wheezing, PEFR% predicted, and Inhaled Corticosteroids). And it significantly increase PEFR. Buteyko Breathing Therapy will improve patients function level and the capacity for independent living by decreasing the severity of asthma symptoms and recurrence of asthma attacks.’

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6. Buteyko Breathing Technique Reduces Hyperventilation Induced Hypocapnoea and Dyspnoea after Exercise in Asthma. 2009. Austin G, Brown C, Watson T, Chakravorty I, PULMONARY REHABILITATION. Physiotherapy School, U Hertfordshire, Hatfield, Herts, United Kingdom.

“Our study demonstrated the hypothesised physiology of BBT, improving hyperventilation induced hypocapnoea and breathlessness, following maximal exercise. By teaching patients to reduce hypernoea of breathing (the rate &depth), BBT may reduce asthma symptoms and improve exercise tolerance and control.”

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7. A randomized controlled trial of the Buteyko technique as an adjunct to conventional management of asthma. Respiratory Journal; 2008 May;102(5):726-32. University of Calgary, Canada. (Cowie RL, et al)

At six month follow up the Buteyko group had:

  • Improved asthma control from 40% to 75%
  • 39% of patients decreased inhaled corticosteroids
  • 21% eliminated inhaled corticosteroids

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“I’ve been astonished and also very pleased with the excellent result. There is no disruption of their life at all by their disease: normal activities; not waking at night; not needing to use any reliever medications. It’s just great…75% control is about as good as anyone has got in any study of asthma. The neat thing about it is that it has no side effects. It’s very safe. The Buteyko technique certainly has been shown to be an important adjunct to treatment.”
Dr. Robert Cowie, Resident Respirologist of Foothills Hospital in Calgary and head researcher on the Buteyko Breathing Technique Medical Trial. (October 2004 April 2005)

8. Double blind randomised controlled trial of two different breathing techniques in the management of asthma Thorax. 2006
Aug;61(8):651-656 (Slader et al, 2006)

At week 28; Buteyko Method Group achieved:

  • Reliever medication decreased by 86%
  • Inhaled Corticosteroids decreased by 50%

9. The New Zealand Medical Journal. 2006 May 19; 119(1234)
Buteyko breathing technique and asthma in children: a case series (McHugh et al, 2006)

At 3 months; Buteyko Group achieved:

  • Reliever medication decreased by 66%
  • Inhaled Corticosteroids decreased by 41%

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10. The New Zealand Medical Journal, 2003 Dec 12;116(1187)

Buteyko Breathing Technique (BBT) for asthma: an effective intervention (McHugh et al, 2003)

At 6 months; Buteyko Group achieved:

  • Reliever medication decreased by 85%
  • Inhaled Corticosteroids decreased by 50%

“Conclusions: BBT is a safe and efficacious asthma management technique. BBT has clinical and potential pharmaco-economic benefits that merit further study”

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11. Journal Asthma 2000;37(7):557-64.

A clinical trial of the Buteyko Breathing Technique in asthma as taught by a video. Opat Aj, Cohen MM, Bailey Mj, Abramson Mj.

“Our results demonstrated a significant improvement in quality of life among those assigned to the BBT compared with placebo (p= 0.043), as well as a significant reduction in inhaled bronchodila- tor intake (p = 0.008).”

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12. Medical Journal Australia 1998 Dec 7-21; 169 (11-12)575-578

Buteyko breathing techniques in asthma: a blinded randomized controlled trial.
Simon D Bowler, Amanda Green and Charles A Mitchell

At 3 months; Buteyko Group achieved:

  • Reliever medication decreased by 90%
  • Inhaled Corticosteroids decreased by 49%

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he above study found that when the breathing volume of asthmatics decreased from 14 litres to 9.6 litres per minute, their symptoms reduced by 70%, the need for rescue medication decreased by 90%, and the need for preventer steroid medication decreased by 49%.

13. Systematic review of the effectiveness of breathing retraining in asthma management. Expert Review Respiratory Medicine.2011;5(6)Burgess J, Ekanayake B, Lowe A, Dunt D, Thien F C Dharmage S.

The BBT has been the most widely publicized among the CAM techniques used in asthma management. Individual studies using BBT consistently demonstrated a reduction in asthma medication use, and together with respiratory physiotherapy studies, often showed an improvement in AQOL and the subjective experience of asthma symptoms. However, there was no significant improvement in lung function in any of the BBT studies to account for the positive results. This was supported by the results of meta-analyses, which failed to show an effect of these techniques using pooled estimates. While it is possible that the deep inspiration required for lung function testing might induce bronchoconstriction [56] and override any beneficial effect from BBT, it is also possible that the studies were inadequately powered to detect changes in lung function parameters. Larger studies might reveal an effect. A meta-analysis of the studies that explored the postulated underlying mechanism proposed in BBT showed a significant increase in end-tidal CO2 in the active intervention arm.

Critics of BBT argue that medication reduction could be due to the therapist’s influence and it is difficult to evaluate that possibility. On the other hand, there was no evidence of a detrimental effect on asthma control with reduction in medication usage and to some extent, there might have been an improvement in symptoms. Longer follow-up is needed to show that improvement in asthma control as measured by medication usage is sustained for a duration that is clinically meaningful, and that BBT has no adverse effects. Despite the lack of evidence for physiological change to account for the observed benefits, a decrease in medication use could be useful considering the possible systemic effects of ICS use [57,58].

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